电子垃圾拆解区人群甲状腺激素水平改变的Meta分析

doi:10.3969/j.issn.1004-616x.2017.04.004

Abstract

Abstract:

OBJECTIVE: To evaluate correlations between serum thyroid hormone levels and exposure to toxic substances from e-waste dismantling regions. METHODS: Randomized-control studies on correlations between serum thyroid hormone levels and exposure to toxic substances from e-waste dismantling areas that were reported on PubMed,Web of Science,Elsevier,CNKI and WanFang Database up to April 2017 were searched and analyzed. The data of the included studies were analyzed using Revman 5.2. RESULTS: 9 randomized-controlled studies were identified including 489 people exposed to toxic chemicals from e-waste dismantling areas and 489 people of control. Serum 1evels of total thyroxine (T4) and free thyroxine (FT4) in the expose groups were significantly lower than those in the control groups (P < 0.05),while there were no significant differences in the serum levels of free triiodothyronine (FT3),total triiodothyronine (T3) and thyrotropin (TSH)(P > 0.05). CONCLUSION: Exposed to toxic chemicals from e-waste dismantling regions may affect the serum level of thyroid hormone.

Key words: e-waste dismantling region, human, thyroid hormones, Meta-analysis

CLC Number:

R994.6

TANG Guangyuan, LIU Ran, YU Xiaojin. Meta-analysis on thyroid hormone levels of populations from e-waste dismantling regions[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(4): 260-265.

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Meta-analysis on thyroid hormone levels of populations from e-waste dismantling regions

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