韭籽多糖对食管癌EC9706细胞增殖和凋亡的影响

doi:10.3969/j.issn.1004-616x.2013.06.006

Abstract

Abstract:

OBJECTIVE: To investigate the effects of Leek seed polysaccharide on the proliferation and apoptosis of human esophagus cancer cell EC9706. METHODS：Flow cytometry，Hoechst33258 staining，transmission electron microscope and DNA gel electrophoresis were used. RESULTS：Proliferation of EC9706 cells was significantly inhibited by Leek seed polysaccharide at the dose of 40 μg/mL(P<0.05). Moreover，after 48 hour of treatment by Leek seed polysaccharide，obvious characteristic features of apoptosis and DNA ladder were also induced. CONCLUSION： Leek seed polysaccharide could inhibit EC9706 cell proliferation and induce its apoptosis.

Key words: Leek seed polysaccharide, human esophagus cancer cell EC9706, proliferation, apoptosis

ZHANG Hong-bo，QU Er-jun，YANG Hai-bo，SONG Wei，CHEN Lan-ying. The effects of Leek seed polysaccharide on the proliferation and apoptosis of human esophagus cancer cell EC9706[J]. Carcinogenesis, Teratogenesis & Mutagenesis, doi: 10.3969/j.issn.1004-616x.2013.06.006.

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The effects of Leek seed polysaccharide on the proliferation and apoptosis of human esophagus cancer cell EC9706

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