纳米二氧化钛和纳米氧化锌的Ames试验

doi:10.3969/j.issn.1004-616x.2010.04.013

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2010, Vol. 22 ›› Issue (4): 302-304.doi: 10.3969/j.issn.1004-616x.2010.04.013

Previous Articles Next Articles

Ames test of nano TiO2 and nano ZnO

MA Mao-cai1;HUANG Ping1;YAN Hui2;TAO Yun1;DENG Ya-bin1;LI Dong-Hui1

1.Cancer Research Center, Medical College, Xiamen University, Xiamen 361005; 2. People's Hospital of Haizhu, Guangzhou 510220, Guangdong， China

Received:2010-01-25 Revised:2010-04-21 Online:2010-07-30 Published:2010-07-30
Contact: LI Dong-hui

Abstract

Abstract: OBJECTIVE: To study the potential mutagenicity of two photocatalytic nanomaterials, nano TiO2 and nano ZnO. METHODS: In the plate incorporation test of Salmonella typhimurium, the average colony number of spontaneous revertants of TA97, TA98, TA100, TA102 were set at 5 concentrations. RESULTS: The colony number of revertants for the materials tested did not increase with statistical significance, compared with that of spontaneous revertants. The results of Ames test for the two kinds of nanoparticle were negative. CONCLUSION: The results imply that the two kinds photocatalytic nanomaterials tested did not show potential mutagenicity.

Key words: photocatalytic nanomaterials, Ames test, mutagenicity, nano titanium dioxide, nano zinc oxide

CLC Number:

R994.3

MA Mao-cai, HUANG Ping, YAN Hui, TAO Yun, DENG Ya-bin, LI Dong-Hui. Ames test of nano TiO2 and nano ZnO[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2010, 22(4): 302-304.

[1]	GE Xianmin, LI Bin, HUANG Chaopei, GAO Yuqiu, LUO Hailan, YANG Hui, WANG Yanwu, WEN Pingjing, LAN Guanghua, CHEN Huanhuan, MENG Qin, LUO Liuhong, DENG Yueqin, LIU Shuaifeng, WU Xiuling. Acute oral toxicity and mutagenicity of combined drugs for anti HIV [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(6): 466-469,474.
[2]	HUANG Chaopei, QIN Huiyan, ZHANG Lujuan, WANG Yanwu, HE Li, FU Weizhong. Study on acute toxicity and mutagenicity of Aronia melanocarpa extract in mice [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(6): 474-476.
[3]	ZHOU Su, LI Rui, ZHU Hongyan, ZHANG Zhichao, FANG Jing, TANG Liming. An optical density method for determining bacterial concentrations in the Salmonella typhimurium reverse mutation assay [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(1): 62-66.
[4]	ZHENG Kai, WANG Bingyu, XU Xinyun, GENG Hong, HUANG Haiyan, LIU Wei, LONG Dingxin. Mutagenicity of PM_2.5 samples from Shenzhen and Taiyuan [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 483-487.
[5]	CAO Yiyi, XI Jing, TANG Weifeng, YOU Xinyue, LIU Weiying, LUAN Yang. Genotoxicity evaluation of triclosan in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(1): 71-75.
[6]	JIANG Yi, JIA Xiaohui, LI Peining, CHEN Xiujuan, LIU Donghong, LIU Xiangmei. Ames mutagenicity assay on five plastic surface chemicals in racetrack [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(4): 309-312.
[7]	YUAN Ye, CHEN Dandan, JING Shufang, YU Yongsheng, CHEN Jianheng, WU Chunqi, SHI Chang. Mutagenic effects of N-(n-butyl)-thiophosphorictriamide in somatic and germ cells of mice [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(6): 432-437.
[8]	SHAN Chun, HU Peili, ZHANG Luyong, LIU Ting, LIN Fei. Different induction and cryopreservation methods on metabolic activities of rat liver S9 [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(5): 388-392.
[9]	CAO Yiyi, LIU Qian, XI Jing, MA Leilei, LIU Xiaojian, LUAN Yang. Comparative evaluation of mutagenicity of four aristolochic acids components using the Ames fluctuation test [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(5): 398-402.
[10]	GAO Mei, CAO Chong, YING Yong, MA Hui, JIA Qingwen. Comparison of different inductionmethods on activity of rat liver microsomal enzymes [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(4): 269-272.
[11]	YING Jian, HAO Binxiu, MENG Qingjia, CHEN Ran, WANG Liming, WANG Chunling. Acute toxicity and genotoxicity of crude water extracts from tea mistletoe Viscum Liquidambaricolum Hayata [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(4): 306-309,324.
[12]	LUO Xueting, CAI Qijun, ZHAO Bo, CHEN Weimin, CHEN Xiao, ZHANG Xiaowen. Evaluation of acute and genetic toxicity of Zihe herbal solid beverage in mice [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(4): 302-305.
[13]	TANG Jiao, ZHAO Min, YANG Ying, LI Qing, HUANG Junming, YANG Xingfen. Study on acute toxicity and mutagenicity of Panaxnotoginseng [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(1): 66-68,72.
[14]	YAN Jiuming, YUE Qianlan, JIA Zhenchao, LI Yan, ZHANG Lishi. General toxicity and mutagenic effects of Mulberry-Astragalus capsule [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(6): 472-476.
[15]	LIU Tiantian, SHEN Chunlin, LÜ Lulu, ZHANG Tianbao. Genotoxicity of PAMAM dendrimer (ethylenediamine core) generation 5.0 solution [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(5): 378-382.

Ames test of nano TiO2 and nano ZnO

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments