海藻多糖的抗突变性研究

doi:10.3969/j.issn.1004-616x.2001.01.014

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2001, Vol. 13 ›› Issue (1): 42-043.doi: 10.3969/j.issn.1004-616x.2001.01.014

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STUDY ON THE ANTIMUTAGENICITY OF SEAWEED POLYSACCHARIDES

XIANG Hua1, ZHAO Jian - zhong2, BO Lin2

1. Hygiene and Anti - epidemic Station of Hangzhou, Hangzhou 　310006, China; 2. Department of Cytobiology, College of Biological Sciences, Zhejiang University, Hangzhou 310009, China

Received:2000-01-10 Revised:2000-06-15 Online:2001-01-30 Published:2001-01-30

Abstract

Abstract: Purpose and Methods : In order to characterize the antimutagenic effect of seaweed polysaccharides (SP) , the mouse bone marrow micronucleus test and mouse sperm malformation test were conducted. Results :The result s showed that the f requencies of micronucleus and abnormal sperms induced by cyclophosphamide (CP) were reduced significantly by SP( P < 0 ,01) . Conclusion : It is suggested that SP can significantly inhibit the mutagenesis of germ cells and stomatic cells induced by CP.

Key words: seaweed polysaccharide, cyclophosphamide, micronucleus test, sperm deformity

CLC Number:

R15113
R99

XIANG Hua, ZHAO Jian - zhong, BO Lin. STUDY ON THE ANTIMUTAGENICITY OF SEAWEED POLYSACCHARIDES[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2001, 13(1): 42-043.

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STUDY ON THE ANTIMUTAGENICITY OF SEAWEED POLYSACCHARIDES

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